Lupus Drugs

Rituxan Lupus as a New Method of Treatment

Rituxan lupus is becoming an option for the treatment of the disease for several reasons. One of the reasons is that increased or abnormal B-cell activity is a factor in lupus and other autoimmune diseases and can be treated with drugs such as rituxan. Indeed, rituxan has the ability to decrease the number of B defective B cells attacked by lupus related symptoms.

The rituxan mode of action against B cells includes attacking the B cells that are still in transition phase, or in an adolescent phase. These cells are unable to participate in the immune system response to intruders thus the attack by the drug.   Doctors have noticed that patients who took rituxan improved and had more healthy B cells.

Meanwhile, these patients have few mature cells thus their immune system is unable to mount a responsive attack against bacteria and viruses. It thus becomes important to monitor this group of patients closely for risks of infections.

On the …


What Are the Causes and Symptoms of Lupus Eryth?

Systemic lupus eryth is a type of the SLE disease which causes the body’s immune system to attack healthy tissue. This mistaken attack can lead to long-term chronic inflammation.

Reports have showed that SLE is much more common in women than men and may occur at any age. Meanwhile, the disease appears most often in people between the ages of 10 and 50. Finally, the African-Americans and Asians racial groups are affected more often than people from other races.

Lupus related symptoms vary from person to person and the severity depends on the type and degree of the disease. The majority of people diagnosed with lupus eryth have been complaining of joint pain and swelling while some develop arthritis. Some of the joints that are frequently affected joints include the fingers, hands, and knees.

Other common SLE related symptoms include chest pain. Chest pain for lupus patients usually occurs when fatigue occurs when taking a deep breath. Some signs of …


What is the Role of SLE (Lupus) Cyclophosphamide in the Treatment of Lupus?

For those affected with lupus cyclophosphamide is one of the most effective cytotoxic in the management of lupus renal disease. In the treatment of SLE cyclophosphamide plays an important role that has been determined in two controlled studies.

In the first study, patients were treated with doses of prednisone which is one form of cytotoxic. The majority of patients, about 40 percent progressed slowly to a better stage of the lupus disease.

In the second study, a group of patients were randomly assigned to receive low doses of cyclophosphamide during a short period of time. This period of time was determined by the advanced stage of the disease that is for about 3 weeks. Reports from these studies showed that low doses of cyclophosphamide given a short period of time were successful in controlling levels of ESRD.

A third study was centered toward people with central nervous system problems due to lupus. The study compared people who took cyclosphosphamide intravenously …


Lupus Cytoxan as a Form of Chemotherapy

While the main use of Cytoxan (cyclophosphamide) is as a chemotherapy agent, it is used primarily as an immunosuppressive for treating lupus. For people diagnosed with lupus cytoxan are considered for treatment because of two main reasons: they are potent drugs and help control disease activity in major organs, and they may reduce or eliminate the need for steroids and their associated side effects.

In a randomized study, researchers found that 22.5% of patients taking other lupus curing drugs such as CellCept had abnormal renal measurements that returned to normal and stayed normal after a long period of time compared with 5.8% of patients treated with Cytoxan. In addition, patients taking CellCept had more hospitalizations or severe infections than patients on Cytoxan as reported in the Nov. 24 issue of the New England Journal of Medicine.

 

SLE Cytoxan Work Mechanism

 

Cytoxan for lupus can be given orally in the form of tablets. Meanwhile, the drug is more …


Hydroxychloroquine Lupus as a New Form of Treatment

Hydroxychloroquine lupus is often prescribed for mild to moderate cases of lupus related symptoms and may be effective in preventing skin flares and possibly blood clots caused by the disease. Doctors also give hydroxychloroquine SLE to lupus patients in conjunction with low doses of corticosteroids.

A study recently reported from Spain found that antimalarial drugs such as hydroxychloroquine not only helped control lupus but patients who took the drug also lived longer than other lupus patients who did not take hydroxychloroquine.

Since the early 1990s, several studies performed by the LUMINA (LUpus in MInorities: NAture vs. nurture) have tracked a group of patients in the US. At the time this study was conducted, the LUMINA study included information on 218 Hispanics, 220 African Americans, and 170 Caucasian patients. Of those 608 patients, 61 had died from various causes.

The researchers focused on the records of the 61 patients who had died, comparing those who were taking hydroxycholoroquine to those who …


Dhea Lupus Treatment for Women

Supplementing lupus treatments for women with dehydroepiandrosterone (DHEA lupus) can be helpful according to a report in Arthritis and Rheumatism (2002; 46:2924–7). This report confirms the results of an earlier study demonstrating that with DHEA SLE can be controlled.

DHEA is a steroid hormone manufactured in the adrenal glands, ovaries, and testes. Moreover, the immune system tends to be overly aggressive in individuals with lupus. Therefore, the use of DHEA can help alleviate that activity. This action has been showed in a particular genetic strain of mice that developed a disease resembling lupus. The administration of DHEA delayed the onset and reduced the severity of the disease.

In another study reported in the Arthritis and Rheumatism report, 120 women with active lupus were randomly selected. One half of the group was assigned to receive 200 mg of DHEA per day while the other received a placebo for 24 weeks. During the study, 33.9% of the participants in the …


Lupus Corticosteroids, SLE Corticosteroids as a Way to Treat Lupus

For people affected with lupus corticosteroids are known to suppress infection of the immune system and reduce inflammation caused by lupus. This ability allows SLE corticosteroids to control lupus related symptoms such as inflammation, pain, and tissue damage throughout the body. Many of the above symptoms result from inflammation in various tissues of the body. Moreover, cortisone which is a steroid manufactured naturally by the body’s adrenal glands has been found to have a distinct anti-inflammatory effect.

Doctors have tried to find the right dose of steroids (taken daily or on alternate days) that is low enough to avoid serious side effects but high enough to control symptoms. Such doses would have to be taken either daily or on alternate days depending on the patients at hand. One alternative would be to start at a higher dose and then reduce the dose gradually after your symptoms have been controlled. If the dose that controls symptoms causes unacceptable side effects, another …


What is the Method of Action of Lupus (Sle) Azathioprine?

Lupus azathioprine is an immunosuppressant drug often used in lupus patients in addition to or instead of steroid therapy. Immunosuppressive such as SLE azathioprine are potent drugs that help control the disease’s activity in major organs. Azathioprine may also reduce/eliminate the need for steroids. Azathioprine is mostly used on patients who have major organ involvement, severe muscle inflammation, or intractable arthritis.

SLE azathioprines are good agents for suppressing any arm of the immune system, like T cells or B cells. Moreover, azathioprines can suppress transplanted organ rejection, the making of antibodies, or the attack of certain cells, viruses or tumors.

The introduction of azathioprine in clinical practice was first introduced by Sir Roy Calne, the British pioneer in transplantation. Following the work done by Sir Peter Medawar in discovering the immunological basis of rejection of transplanted tissues and organs, Calne introduced 6-mercaptopurine as an experimental immunosuppressant for kidney transplants and cardiac transplantation for lupus patients. For many years, dual therapy …


Lupus Antibiotics as a New Therapy Option

For patients diagnosed with lupus antibiotics therapies are partially based on the theory that inflammatory rheumatic diseases such as lupus are caused by mycoplasmas and other bacterial L forms. The usage of low dose of antibiotics can be aimed at the source of the disease.

This theory and the antibiotic therapy for the treatment of lupus was developed by Dr. Thomas McPherson Brown, the founder of The Arthritis Institute who successfully treated over 10,000 patients with this therapy.

When antibiotics are taken by lupus patients, the first method of action is the destruction of mycoplasmas. At that moment, the patient’s own defense system is able to work correctly because it has fewer microbes to fight which creates less inflammation in the tissues and the lupus related symptoms to decrease in intensity.

It is important for lupus patients to have a committed mind set before seeking a doctor who will work with them in trying this therapy. It should be understood …


Why Is Lupus Aspirin Used In Lupus Treatment?

For people affected with lupus aspirin can be effective in treating malaise and other headaches caused by lupus. Indeed, aspirin has pain-reducing, anti-inflammatory, and anticoagulant (blood-thinning) properties that can help control some of the symptoms of lupus.

Low doses of aspirin taken once a day may help reduce the risk of blood clots and miscarriage in lupus patients who have antiphospholipid antibodies. It is possible that your doctor may recommend that you take one low dose of aspirin daily if your type of lupus is appropriate for the intake of aspirin.  This recommendation is common because low doses of aspirin have been shown to lower the potential for clot-forming blood cells that stick together in narrow blood vessels. Low doses of aspirins are often grouped with antiplatelet medications because they help treat certain lupus symptoms such as: fevers, headaches, muscle aches, malaise, arthritis, & serositis.

 

How Can Aspirin’s Mechanism of Action Help with Lupus?

 

For people affect with …


How Does Lupus Ibuprofen Works In Lupus Patients?

The elaboration of a treatment for lupus depends on your signs and symptoms. In certain cases, lupus ibuprofen might be a good treatment option.  Ibuprofen is a form of nonsteroidal anti-inflammatory drugs (NSAIDs) that treats most lupus associated symptoms.  It is important to remember that ibuprofen may contain inactive ingredients, which can cause allergic reactions or other problems.

When prescribing Ibuprofen, your physicians would determine first the degree of advancement of your type of lupus. Since Ibuprofen has a dose-dependent duration of action of approximately four to eight hours, it is recommended to use the drug once or twice daily. The recommended dose is generally 1,200 mg. This last dose is considered the maximum daily dose for children and other adults. The agreed upon maximum among lupus professional is 800 milligrams per dose or 3200 mg per day.

 

Primary Role of SLE Ibuprofen

 

The primary goal of using ibuprofen as a treatment option for lupus is to prevent flares. The …


Lupus (SLE) MMF as a New Treatment Option

For people suffering with lupus MMF (Mycophenolate mofetil) is intended to prevent rejection of organ transplants. SLE MMF can be taken as a pill which helps the active ingredients of the treatment appear in the blood. Several studies of lupus patients who were subject to MMF have shown that different levels of MPA were found. According to the studies, these different levels were due in part to the type and degree of the disease as well as the type of immunosuppressive drugs the patients took. Moreover, the studies showed that the level of MPA in the blood can affect the proper functioning of any immunosuppressive medicine in preventing transplant rejection. The level of MPA also has an effect on the amount of side effects such as low white blood cell counts and intestinal disorders experienced by lupus patients. For the above reasons, many doctors will check the level of MPA in patients’ blood in order to predict how successful the …


What is a Lupus Anticoagulant?

A lupus anticoagulant is typically found in someone who has this particular autoimmune disorder. This anticoagulant can keep someone’s blood from clotting normally. This problem can be found by doing a lupus anticoagulant blood test. If this shows up in someone’s blood, is does not necessarily mean they have lupus. A medical professional will want to run other tests and ask about other symptoms as well before making an official diagnosis and starting a treatment plan.

Some lupus anticoagulant symptoms including having numerous blood clots and having many miscarriages. People who already have lupus are at a higher risk of having these anticoagulants in their blood. It may be discovered during a routine blood test. Treatment may be required for lupus anticoagulant, but if a person doesn’t experience any symptoms, medications may not be required. However, the condition should be monitored and recorded in a patient’s chart in case symptoms do appear in the future. The most common lupus anticoagulant …


Detecting A Lupus (sle) Antibody

When a medical professional is trying to make a diagnosis of lupus or sle (systemic lupus erythematosus), a blood test is usually done. This is to check for a lupus antibody. The presence of a sle antibody will usually tell a medical professional that lupus could be present in the body. However, just because there are antibodies in the blood does not mean that the disease is active. A medical professional will use the tests as well as a patient’s symptoms in order to make a diagnosis of lupus, since antibodies are not a conclusive way to diagnose the disease.

The symptoms of lupus are very important in order for a medical professional to diagnose the problem. This is because blood tests are not always accurate, and antibodies will not always show up on a test, since they can come and go.  Some of the most common symptoms of lupus are fatigue, widespread joint pain, fever, weight changes, and …


A New Treatment – Benlysta Lupus

New medications are constantly being researched for all kinds of diseases and disorders, including lupus and sle, or systemic lupus erythematosus. One medication that has recently been approved for use by the FDA is Benlysta lupus. It is the first new lupus medication to be approved in 50 years, making it a new landmark in the field. While Benlysta may not work for all patients who have lupus, it can help some people to reduce their symptoms and improve their overall quality of life. Taking Benlysta can help patients reduce the need to take steroids over a long period of time, reducing their risk of side effects from these medications.

The drug Benlysta can help people with mild to moderate types of lupus experience less flare ups.  This is because the drug is an immunosuppressant.  Lupus is a disease that can turn the body’s own white blood cells against the body, making it an autoimmune disease. Benlysta works by …


Using Lupus (sle) Rituximab For Treatment

Prescription medications can be very useful in treating lupus and sle, or systemic lupus erythematosus. One newer drug is lupus Rituximab, and it is an intravenous type of medication. While sle Rituximab has not been shown to be helpful for all types of lupus, it has been shown to have specific benefits for patients with lupus nephritis and refractory systemic lupus erythematosus.  Because Rituximab is a more aggressive form of medication, it is usually used if other types of treatment aren’t working. Easier medications to take, such as oral pills, will usually be tried first. This medication can also be used if someone is in danger of going into kidney failure if they do not get immediate, aggressive treatment.

Rituximab must be introduced to the body slowly in order to make sure there are not going to be any serious side effects. This means that the first treatment session could last several hours. It is important to find a …


Finding Relief with Cellcept Lupus

In order help reduce the symptoms that occur with lupus, many doctors will recommend using a prescription medication. One commonly used medication is Cellcept lupus. This medication will help to treat many of the symptoms that are associated with lupus, including inflammation, joint pain, fatigue, sore throat, and swollen glands. Since lupus, particularly lupus nephritis, attacks the body’s organs such as the kidneys, this medication is especially useful because it works as an immunosuppressant. An immunosuppressant drug works by controlling the disease and suppressing the disease in certain organs. In the case of lupus, it can also reduce the need for the use of steroid medications, which can have a lot of different side effects, especially when used long term.

Cellcept comes in the form of oral pills.  It comes in several different dosages, so it can be catered to an individual’s needs. There is a generic form of the drug available called mycophenolate mofetil. It is available through …


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